Guzey misquotes Hemmeter et al re established antidepressant therapy

Nov 01, 2024 · By Dennis Hackethal · Forked from Guzey properly quotes Hemmeter et al re rapid effect of sleep deprivation · Fork · Check another quote

Original text

Nevertheless, SD is the only established antidepressant therapy that acts within hours, and therefore, can be applied in patients with treatment-resistant depression with a chance of approximately 50% of seeing an immediate, although temporary, relief from depressive symptoms without major side effects. In addition, even in patients who do not respond to SD, an elevation of mood insomnia, which is frequently accompanied by depression, may be substantially improved at least in the recovery night. The experience of realizing that depression can be lifted and sleep can improve is very important for the further therapy motivation of treatment-resistant depressed patients. In recent years, we have learned much more about the clinical effects of SD. TSD and PSD are efficient. Both can be combined with antidepressant medication, predominantly serotonergic agents, with bright light therapy and with a phase advance of sleep cycles. All these strategies have been able to provide a chance to stabilize the SD response, at least in a subgroup of patients.
Ulrich-Michael Hemmeter et al, ‘Sleep deprivation in depression’, Expert Rev. Neurother. 10(7), 1109 (2010)

Quote text

SD is the only established antidepressant therapy that acts within hours, and therefore, can be applied in patients with treatment-resistant depression with a chance of approximately 50% of seeing an immediate, although temporary, relief from depressive symptoms without major side effects. … The experience of realizing that depression can be lifted and sleep can improve is very important for the further therapy motivation of treatment resistant depressed patients. … [Sleep deprivation] can be combined with antidepressant medication, predominantly serotonergic agents, with bright light therapy and with a phase advance of sleep cycles. All these strategies have been able to provide a chance to stabilize the SD response, at least in a subgroup of patients.
Ulrich-Michael Hemmeter et al (ibid), as quoted in: Guzey, A. Matthew Walker’s “Why We Sleep” Is Riddled with Scientific and Factual Errors. Guzey.com. 2019 November. Available from https://guzey.com/books/why-we-sleep/. Bold emphasis removed
Ellipsis used (if any): ‘ …’
Found 3 issue(s) using regular expression . and Myers algorithm, underlined in wavy red. 
Nevertheless,‧SD‧is‧the‧only‧established‧antidepressant‧therapy‧that‧acts‧within‧hours,‧and‧therefore,‧can‧be‧applied‧in‧patients‧with‧treatment-resistant‧depression‧with‧a‧chance‧of‧approximately‧50%‧of‧seeing‧an‧immediate,‧although‧temporary,‧relief‧from‧depressive‧symptoms‧without‧major‧side‧effects.‧In‧addition,‧even‧in‧patients‧who‧do‧not‧respond‧to‧SD,‧an‧elevation‧of‧mood‧insomnia,‧which‧is‧frequently‧accompanied‧by‧depression,‧may‧be‧substantially‧improved‧at‧least‧in‧the‧recovery‧night.‧…‧The‧experience‧of‧realizing‧that‧depression‧can‧be‧lifted‧and‧sleep‧can‧improve‧is‧very‧important‧for‧the‧further‧therapy‧motivation‧of‧treatment-‧resistant‧depressed‧patients.‧…‧In‧recent‧years,‧we‧have‧learned‧much‧more‧about‧the‧clinical‧effects‧of‧SD.‧TSD‧and‧PSD‧are‧efficient.‧Both[Sleep‧deprivation]‧can‧be‧combined‧with‧antidepressant‧medication,‧predominantly‧serotonergic‧agents,‧with‧bright‧light‧therapy‧and‧with‧a‧phase‧advance‧of‧sleep‧cycles.‧All‧these‧strategies‧have‧been‧able‧to‧provide‧a‧chance‧to‧stabilize‧the‧SD‧response,‧at‧least‧in‧a‧subgroup‧of‧patients.

Explanation

# Part Valid? Explanation
1 
Nevertheless,‧
 × no Deletions must be indicated, eg by ‘ …’ or [replacement].
2 
SD‧is‧the‧only‧established‧antidepressant‧therapy‧that‧acts‧within‧hours,‧and‧therefore,‧can‧be‧applied‧in‧patients‧with‧treatment-resistant‧depression‧with‧a‧chance‧of‧approximately‧50%‧of‧seeing‧an‧immediate,‧although‧temporary,‧relief‧from‧depressive‧symptoms‧without‧major‧side‧effects.
3 
‧In‧addition,‧even‧in‧patients‧who‧do‧not‧respond‧to‧SD,‧an‧elevation‧of‧mood‧insomnia,‧which‧is‧frequently‧accompanied‧by‧depression,‧may‧be‧substantially‧improved‧at‧least‧in‧the‧recovery‧night.
 ✓ yes Deletion is followed by a valid insertion.
4 
‧…
 ✓ yes Insertion is an ellipsis.
5 
‧The‧experience‧of‧realizing‧that‧depression‧can‧be‧lifted‧and‧sleep‧can‧improve‧is‧very‧important‧for‧the‧further‧therapy‧motivation‧of‧treatment
6 
-
 × no Deletions must be indicated, eg by ‘ …’ or [replacement].
7 
‧
 × no A single added space must either follow or precede a valid insertion.
8 
resistant‧depressed‧patients.
9 
‧…
 ✓ yes Insertion is an ellipsis.
10 
‧
11 
In‧recent‧years,‧we‧have‧learned‧much‧more‧about‧the‧clinical‧effects‧of‧SD.‧TSD‧and‧PSD‧are‧efficient.‧Both
 ✓ yes Deletion is followed by a valid insertion.
12 
[Sleep‧deprivation]
 ✓ yes Insertion is properly bracketed.
13 
‧can‧be‧combined‧with‧antidepressant‧medication,‧predominantly‧serotonergic‧agents,‧with‧bright‧light‧therapy‧and‧with‧a‧phase‧advance‧of‧sleep‧cycles.‧All‧these‧strategies‧have‧been‧able‧to‧provide‧a‧chance‧to‧stabilize‧the‧SD‧response,‧at‧least‧in‧a‧subgroup‧of‧patients.

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